Research Article

miR-26a Potentially Contributes to the Regulation of Fatty Acid and Sterol Metabolism In Vitro Human HepG2 Cell Model of Nonalcoholic Fatty Liver Disease

Figure 4

Effect of miR-26a overexpression on expression of genes involved in lipogenesis. FASN, SCD1, and SREBP1c; β-oxidation CPTA1, CPT2, PPAR-α, PGC1-α, ACOX1, and HADHA; triglyceride synthesis and storage PLIN2, PLIN4, and DGAT1; and expression of genes involved in fatty acid uptake transporters as well as TG excretion key marker genes CD36 and ApoB. Group labels are the same as for Figure 3. Results shown are the mean ± SD ( and ).