Andrographolide Ameliorates Diabetic Cardiomyopathy in Mice by Blockage of Oxidative Damage and NF-κB-Mediated Inflammation
Andro treatment attenuates diabetes-induced myocardial apoptosis. (a) TUNEL-stained sections. Red nuclei indicate apoptotic cells (scale bar = 20 μm). (b) Quantitative analysis of the proportion of TUNEL-positive nuclei. (c) Western blot analysis of p-Akt and cleaved PARP activity, Bax, and Bcl-2. (d) Bax/Bcl-2 ratio. compared to control; compared to DM.