Hydroxytyrosol Ameliorates Endothelial Function under Inflammatory Conditions by Preventing Mitochondrial Dysfunction

Figure 4

HT effects on SOD activity and oxidative damage in stimulated endothelial cells. HUVEC were pretreated with HT (1–30 μmol/L) for 1 h and then stimulated with PMA for further 16 h; afterwards, the activity of MnSOD (a) and lipid peroxidation, followed by MDA production (b), were evaluated. Data are representative of three independent experiments (mean ± SD) and expressed as percentage of PMA-stimulated endothelial cells. versus CTR; versus PMA alone.

(a)

(b)