Enhanced Oxidative Damage and Nrf2 Downregulation Contribute to the Aggravation of Periodontitis by Diabetes Mellitus

Table 3

Multiple linear regression analysis between Nrf2 expression and oxidative stress biomarkers in diabetic periodontitis and diabetes mellitus groups.

Independent variables	Dependent variable Nrf2 expression
	Coef.	Std. err.	value	95% CI
Constant	0.413	0.047	0.013	0.297	0.528
3-NT	−0.026	0.01	0.038	−0.05	−0.002
4-HNE	−0.022	0.004	0.002	−0.032	−0.011
8-OHdG	−0.079	0.026	0.024	−0.144	−0.015
MDA	−0.034	0.006	0.001	−0.049	0.019
SOD	0.719	0.089	<0.0001	0.501	0.937

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