Grape Seed Proanthocyanidin Ameliorates Cardiac Toxicity Induced by Boldenone Undecylenate through Inhibition of NADPH Oxidase and Reduction in the Expression of NOX2 and NOX4

Table 2

Changes in serum lactate dehydrogenase (LDH), creatine kinase (CK), creatine kinase MB (CK-MB), myoglobin, and troponin-T levels in different groups.

	Control	GSPE	Boldenone	Boldenone + GSPE
LDH (U/L)	112.7 ± 8.2^#	106.5 ± 9.1^#	139.1 ± 7.8	123.6 ± 10.5^#
CK (U/L)	769.5 ± 11.6^#	748.8 ± 15.5^#	955.0 ± 16.5	817.3 ± 20.8^#
CK-MB (ng/mL)	0.202 ± 0.05^#	0.211 ± 0.11^#	0.370 ± 0.05	0.315 ± 0.09^#
Myoglobin (ng/mL)	13.8 ± 1.39^#	13.2 ± 0.76^#	16.6 ± 0.42	15.1 ± 1.05^#
Troponin T (pg/mL)	0.016 ± 0.06	0.016 ± 0.03	0.015 ± 0.03	0.016 ± 0.05

Value represents mean ± SEM of 10 rats. Significant difference from the control group at . ^#Significant difference from the Boldenone group at .