Resveratrol-Induced Downregulation of NAF-1 Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine via the ROS/Nrf2 Signaling Pathways

Figure 6

Resveratrol-induced inhibition of NAF-1 enhances the sensitivity of pancreatic cancer cells to gemcitabine. (a–c) Panc-1 and Mia paca-2 cells were treated with gemcitabine (2 μM) and resveratrol (50 μM) for 48 h. Apoptosis was detected by flow cytometry. (e–g) The combined effects of gemcitabine and resveratrol on the colony-forming ability of Panc-1 and Mia paca-2 cells were detected using a colony formation assay. Images are representative of three independent experiments (scale bar: 1 cm). Column: mean; bar: SD. .

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