Granulocyte Colony-Stimulating Factor Alleviates Bacterial-Induced Neuronal Apoptotic Damage in the Neonatal Rat Brain through Epigenetic Histone Modification

Figure 2

G-CSF alleviated the elevation of TNF-α expression levels. Effect of G-CSF on LPS-induced production of TNF-α. The experimental groups are indicated as follows: vehicle-control (C), LPS (LPS), G-CSF (G), and LPS + G (LPS + G) ( animals for each experimental group). The level of TNF-α expression was elevated in the LPS group compared with the control group. There were no significant differences between the LPS + G-CSF and control groups. compared with the vehicle-control group. compared with the LPS group. β-Actin levels performed in parallel served as controls.