Psychological Stress and Cellular Aging in Cancer: A Meta-Analysis

<div>Simplified hypothetical scheme for the role of psychological stress in carcinogenesis and aging. CATs: catecholamines; ROS: reactive oxygen species; O<sub>2</sub><sup>⋅−</sup>: superoxide anion radical; HO<sup>⋅</sup>: hydroxyl radical; H<sub>2</sub>O<sub>2</sub>: hydroxyl peroxide; <sup>1</sup>O<sub>2</sub>: singlet oxygen; NO<sup>⋅</sup>: nitric oxide; ONOO<sup>−</sup>: peroxynitrite; HPA axis: hypothalamic pituitary adrenal axis; SNS: sympathetic nervous signaling.</div>

Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: Psychological Stress and Cellular Aging in Cancer: A Meta-Analysis 