Scutellarin Exerts Hypoglycemic and Renal Protective Effects in db/db Mice via the Nrf2/HO-1 Signaling Pathway
(a) Schematic of the animal experimental protocol and drug administration. Eight weeks of SCU and Met treatment regulated (b) body weight, (c) blood glucose, (d) glucose tolerance, and the levels of (e) glycated hemoglobin, (f) insulin, and (g) pyruvate kinase in serum of db/db mice. Results are represented as (). and in a comparison with the db/m+ mice, ,, and in a comparison with the vehicle-treated db/db mice. SCU: scutellarin; Met: metformin.