Oxidative Medicine and Cellular Longevity / 2019 / Article / Fig 3

Research Article

Exosomes Derived from TIMP2-Modified Human Umbilical Cord Mesenchymal Stem Cells Enhance the Repair Effect in Rat Model with Myocardial Infarction Possibly by the Akt/Sfrp2 Pathway

Figure 3

Effect of huc-exoTIMP2 on post-MI cardiac function. (a) EF%, FS%, LVESd, and LVEDd values at 30 days after injection of exosomes. (b) Representative pictures showing the macroscopic appearance of hearts at 30 days post-MI. Arrows indicate infarcted areas. (c) Heart weight/body weight (HW/BW) ratios in different groups. (d) Representative pictures of H&E and Masson trichrome-stained heart sections in different groups. Scale bar: 50 μm. Blank: rats without surgery; MI+PBS: MI rats treated with PBS; NC: MI rats treated with huc-exoNC; TIMP2: MI rats treated with huc-exoTIMP2. , , and .

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