Exosomes Derived from TIMP2-Modified Human Umbilical Cord Mesenchymal Stem Cells Enhance the Repair Effect in Rat Model with Myocardial Infarction Possibly by the Akt/Sfrp2 Pathway

<div>huc-exo<sup>TIMP2</sup> ameliorated oxidative stress-induced cardiomyocyte apoptosis. (a) TUNEL<sup>+</sup> nuclei in cardiac sections. Scale bar: 50 <i>μ</i>m. (b) The levels of MDA, SOD, and GSH concentrations in the heart tissues of different groups. (c) Immunoblots showing the expression levels of Bcl2, Bax, and pro-caspase-9 in heart tissues of different groups; comparison of quantified protein levels. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Exosomes Derived from TIMP2-Modified Human Umbilical Cord Mesenchymal Stem Cells Enhance the Repair Effect in Rat Model with Myocardial Infarction Possibly by the Akt/Sfrp2 Pathway 

Figure 4 | Exosomes Derived from TIMP2-Modified Human Umbilical Cord Mesenchymal Stem Cells Enhance the Repair Effect in Rat Model with Myocardial Infarction Possibly by the Akt/Sfrp2 Pathway 