CIAPIN1 Targeted NHE1 and ERK1/2 to Suppress NSCLC Cells’ Metastasis and Predicted Good Prognosis in NSCLC Patients Receiving Pulmonectomy
Table 3
Univariate analysis of the association between clinical characteristics and survival in patients with NSCLC ( is considered statistically significant).
Variables
Univariate analysis
Multivariate analysis
Chi-square
HR (95% CI)
OS
Age (<60 years vs. ≥60 years)
0.171
0.679
Gender (male vs. female)
0.090
0.765
Smoking status (never smoker vs. smoker)
2.760
0.097
Histological type (squamous cell carcinoma vs. adenocarcinoma)
2.819
0.093
TNM stage (I, II, and III)
4.236
0.040
0.644 (0.198-2.100)
0.465
Tumor size (≤3 cm vs. >3 cm)
6.874
0.009
0.397 (0.164-0.961)
0.040
Lymphatic invasion (negative vs. positive)
11.712
0.001
0.247 (0.086-0.704)
0.009
CIAPIN1 expression (low vs. high)
7.401
0.007
3.120 (1.084-8.977)
0.035
DFS
Age (<60 years vs. ≥60 years)
0.003
0.959
Gender (male vs. female)
0.106
0.745
Smoking status (never smoker vs. smoker)
2.113
0.146
Histological type (squamous cell carcinoma vs. adenocarcinoma)