Oxidative Medicine and Cellular Longevity / 2019 / Article / Fig 6

Research Article

p53-Mediated PI3K/AKT/mTOR Pathway Played a Role in PtoxDpt-Induced EMT Inhibition in Liver Cancer Cell Lines

Figure 6

PtoxDpt treatment induced ROS production at different conditions and alteration in EMT markers. (a) 20 h treatment: A1: 0.75% DMSO; A2: 1.56 μM PtoxDpt; A3: 1.56 μM mM NAC; A4: medians of fluorescence in different groups. (b) 2 h treatment in the presence of 10 ng TGF-β1: B1: 0.75% DMSO; B2: 1.56 μM PtoxDpt; B3: 1.56 μM mM NAC; B4: Western blotting analysis of EMT markers.
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