Research Article
The Impact of High-Fat Diet on Mitochondrial Function, Free Radical Production, and Nitrosative Stress in the Salivary Glands of Wistar Rats
Table 1
General characteristics of rats.
| | C | HFD | |
| | Final body weight (g) | | | <0.0004 | | BMI (g/cm2) | | | <0.002 | | Fasting glucose (mg/dL) | | | <0.0001 | | Fasting insulin (μU/mL) | | | <0.0001 | | HOMA-IR index | | | <0.0001 | | Plasma FFA (μmol/L) | | | <0.0001 | | Food consumption (g/day) | | | <0.04 | | Energy intake (kJ/day) | | | <0.0006 | | Parotid gland weight (mg) | | | <0.03 | | Submandibular gland weight (g) | | | ns | | NWS (μL/min) | | | ns | | SWS (μL/min) | | | <0.0004 | | Parotid gland total protein (μg/mL) | | | <0.0006 | | Submandibular gland total protein (μg/mL) | | | <0.003 |
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C: control group; HFD: high-fat diet group; BMI: body mass index; HOMA-IR: homeostasis model assessment of insulin resistance; FFA: free fatty acids; NWS: nonstimulated salivary flow; SWS: stimulated salivary flow.
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