Cerium Oxide Nanoparticles Regulate Insulin Sensitivity and Oxidative Markers in 3T3-L1 Adipocytes and C2C12 Myotubes

Figure 1

Cell metabolic activity in RAW 264.7 macrophages (a), 3T3-L1 adipocytes (b), and C2C12 myotubes (c) measured with MTT assay at 24 h after CeO₂ NP treatment at 10, 20, 50, and 100 μg/ml doses in percentage compared to nontreated control (NTC). White shapes: control medium; black shapes: inflammation in macrophages activated with lipopolysaccharide (LPS), adipocytes, and myotubes treated with conditioned medium (CM); , control vs. inflammation; , CeO₂ NPs vs. control; CeO₂ NPs vs. inflammation; data (/group) are expressed as mean (SEM).

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