The Preventive Effects and the Mechanisms of Action of Navel Orange Peel Hydroethanolic Extract, Naringin, and Naringenin in N-Acetyl-p-aminophenol-Induced Liver Injury in Wistar Rats

Table 4

Effects of the navel orange peel ethanolic extract, naringin, and naringenin on serum TNF-α and IL-4 levels of APAP-administered Wistar rats.

Parameter	TNF-α (pg/ml)	IL-4 (pg/ml)
Treatments
Normal control
APAP	^a	^a
APAP + navel orange peel extract	^ab	^ab
APAP + naringin	^ab	^ab
APAP + naringenin	^ab	^ab

Data are expressed as mean ± SE of . ^aSignificantly different from the normal value at . ^bSignificantly different from the APAP value at .