Research Article
Morinda citrifolia and Its Active Principle Scopoletin Mitigate Protein Aggregation and Neuronal Apoptosis through Augmenting the DJ-1/Nrf2/ARE Signaling Pathway
Table 1
(a) Impact of MCE on antioxidant defense system. Values are expressed as for six animals in each group. SOD: units/mg protein. One unit is equal to the amount of enzyme that inhibits the pyrogallol autoxidation by 50%; CAT: μmoles of H2O2 consumed/min/mg protein; GPx: μg of GSH consumed/min/mg protein; GR: nmoles of NADPH oxidized/min/mg protein; GST: μmoles of CDNB conjugate formed/minute/mg protein; GSH: nmoles/mg protein. (b) Impact of MCE on the activities of Nrf2/ARE downstream enzymes. Values are expressed as for six animals in each group. γGCLC: millimoles of NADH oxidized/min/mg protein; NQO1: nmoles DCPIP utilized/min/mg protein; HO-1: nmoles of bilirubin/h/mg protein. Statistical significance () was calculated by Student-Newman-Keuls and least significant difference post hoc test, where represents control vs. other groups, represents rotenone vs. LD, MCE.
(a) Impact of MCE on antioxidant defense system | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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(b) Impact of MCE on the activities of Nrf2/ARE downstream enzymes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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