Research Article

Phosphatidylcholine Extends Lifespan via DAF-16 and Reduces Amyloid-Beta-Induced Toxicity in Caenorhabditis elegans

Table 1

Effect of phosphatidylcholine on lifespan of C. elegans.

PC (mg/l)Mean lifespan (day) value1% effect2

1st experiment013.8
1017.7<0.00128.8
10016.8<0.00122.2
2nd experiment018.6
1021.8<0.00117.3
10020.30.0219.2
3rd experiment018.7
1020.10.0787.2
10021.30.00113.6

value was calculated using the log-rank test by comparing the survival rate of the untreated control group (0 mg/l phosphatidylcholine) to that of the phosphatidylcholine-treated group (10 or 100 mg/L phosphatidylcholine). 2% effects were calculated by , where is the mean lifespan of the phosphatidylcholine-treated group and is the mean lifespan of the untreated control group. PC: phosphatidylcholine.