Research Article

Leptin and Adiponectin Signaling Pathways Are Involved in the Antiobesity Effects of Peanut Skin Extract

Figure 4

Effects of PSE on the hypothalamus of obese mice. Gene expression of leptin, leptin receptor, ADR1, ADR2, AgRP, and NPY in obese mice after PSE treatment (a). The changes of adiponectin and NPY (b) and leptin proteins (c) in the hypothalamus of obese mice after PSE treatment. Sample numbers are seven or eight, and the values represent the . #, ##, and ### represent the significant difference comparison with the normal control at , , and . , , and indicate the significant difference comparison with the HFD group at , , and .
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