Modulation of Antioxidant Potential with Coenzyme Q10 Suppressed Invasion of Temozolomide-Resistant Rat Glioma In Vitro and In Vivo

Figure 1

Combined effect of CoQ10 and TMZ on RC6 cell growth. Cell viability was determined using SRB assay 72 h after treatment. IC50 values for each CoQ10 concentration are included next to the graph. The average ±SEM was obtained from four independent experiments. Statistical significance: 5 μM CoQ10 to 0 μM CoQ10, ($) and ($$$); 10 μM CoQ10 to 0 μM CoQ10, (##) and (###); 25 μM CoQ10 to 0 μM CoQ10, () and ().