CO+V: control plus vehicle (); SIM 4: control plus simvastatin 4 mg/kg (); NASH+V: NASH plus vehicle (); NASH+SIM 4: NASH plus simvastatin 4 mg/kg (). The data are expressed as the (S.D); DI: damage index, which can range from 0 (completely undamaged, ) to 400 (with maximum damage ). CO+V versus NASH+V. # versus CO+V and SIM 4. $ versus NASH+V. versus CO+V and SIM 4.