Research Article

Bailcalin Protects against Diabetic Cardiomyopathy through Keap1/Nrf2/AMPK-Mediated Antioxidative and Lipid-Lowering Effects

Figure 2

BAI alleviated T2DM-induced cardiac fibrosis: (a) Masson staining for cardiac fibrosis in the mouse left ventricle, (b) the calculated fibrosis area among different groups, and (c) the mRNA expression of fibrosis-associated biomarkers, including TGF-β, collagen I, collagen III, CTGF, MMP2, and MMP 9. . VEH: vehicle; DM: diabetes mellitus; BAI: Bailcalin. compared with the VEH or BAI group; # compared with the DM group.