The Role of Traditional Chinese Medicine in the Regulation of Oxidative Stress in Treating Coronary Heart Disease

Table 2

The role of traditional Chinese medicine (TCM) in the regulation of reactive oxygen species (ROS) in ischemic heart failure and angina.

Type of disease	Type of TCM	TCM (molecular formula)	Type of study	Mechanism of action	References
Ischemic heart failure	Patented drugs from traditional Chinese medicine	Qi-shen-yi-qi	In vivo	Recovering angiotensin II-NADPH oxidase-ROS-MMP pathways	Li et al. [114]
		Tongxinluo	In vivo	Activation of the VEGF/Akt/eNOS signaling pathway	Wang et al. [117]
		YiQiFuMai powder injection	In vivo	Ameliorating cardiac function and structure damage, oxidative stress, and cell apoptosis and inhibiting the MAPK signaling pathways	Pang et al. [121]
Stable angina		Tongmai Yangxin pill	In clinic	Attenuating oxidative stress and inflammation	Cai et al. [127]

ROS: reactive oxygen species; MMPs: matrix metalloproteinases; VEGF: vascular endothelial growth factor; Akt: serine/threonine kinase; eNOS: endothelial nitric oxide synthase; MAPK: mitogen-activated protein kinase.