Research Article

Protocatechuic Acid-Mediated miR-219a-5p Activation Inhibits the p66shc Oxidant Pathway to Alleviate Alcoholic Liver Injury

Table 2

miRNAs are reported to be downregulated in ALD, and based on the TargetScan database, certain miRNAs may target p66shc.

Aberrantly expressed miRNAs in ALD

Aberrantly expressed miRNAsmiR-21miR-27amiR-34amiR-122miR-125
miR-126miR-155miR-182miR-183miR-199a
miR-200amiR-214miR-217miR-219miR-320
miR-375miR-486miR-513miR-571miR-652
miR-705miR-1224let-7b
Decreased miRNAsmiR-125miR-126miR-182miR-183miR-199a
miR-200amiR-214miR-219miR-652let-7b
TargetScanmiR-183miR-214miR-219let-7b
ConservationmiR-183-5p.2miR-219a-5p