Oxidative Medicine and Cellular Longevity / 2019 / Article / Fig 3

Research Article

Bloom Syndrome Protein Activates AKT and PRAS40 in Prostate Cancer Cells

Figure 3

Selected phosphorylated nodal proteins in PC-3 and BLM KO PC-3 cells. (a) Phosphorylated nodal proteins investigated in this study. (b) Expression of phosphorylated signaling proteins in two different PC-3 cell lines. (c) Quantitation of AMPKα, HSP27, Bad, SAPK/JNK, and PARP expression levels revealed their upregulation in BLM KO PC-3 cells, while AKT (Ser473) and PRAS40 (Thr246) expression levels were significantly downregulated (; and ).
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