Oxidative Medicine and Cellular Longevity

Research Article

Bloom Syndrome Protein Activates AKT and PRAS40 in Prostate Cancer Cells

Table 2

Target pathways identified by KEGG enrichment.


Map name	Map ID	Input number	Input proteins	value

Pathways in cancer	K05200	8	Q02750\|P31749\|P50150\|P25445\|P06753\|Q9Y4K3\|Q15147\|P11166
Thyroid hormone signaling pathway	K04919	5	P11166\|Q02750\|P31749\|Q15147\|P49815
mTOR signaling pathway	K04150	5	Q02750\|Q8TB45\|P49815\|P31749\|Q96B36
Adrenergic signaling in cardiomyocytes	K04261	5	Q15173\|P31749\|P06753\|Q9BXT2\|Q15147
p53 signaling pathway	K04115	4	P25445\|P27701\|P31350\|P49815
PI3K-Akt signaling pathway	K04151	6	Q02750\|P31749\|P50150\|P22105\|Q15173\|P49815
Chagas disease (American trypanosomiasis)	K05142	4	P25445\|P31749\|Q9Y4K3\|Q15147
MAPK signaling pathway	K04010	5	P31749\|P25445\|Q02750\|Q9BXT2\|Q9Y4K3
Cholinergic synapse	K04725	4	Q02750\|P31749\|P50150\|Q15147
Sphingolipid signaling pathway	K04071	4	Q15173\|Q02750\|P31749\|Q15147
AMPK signaling pathway	K04152	4	Q15173\|P49815\|P31749\|Q96B36
Dopaminergic synapse	K04728	4	Q15173\|P31749\|P50150\|Q15147
Phospholipase D signaling pathway	K04072	4	Q02750\|P31749\|Q15147\|P49815
Chemokine signaling pathway	K04062	4	Q02750\|P31749\|P50150\|Q15147

value < 0.05, the number of target proteins involved in the pathway ≥4.