Oxidative Medicine and Cellular Longevity / 2019 / Article / Fig 1

Research Article

Suppression of Alzheimer’s Disease-Like Pathology Progression by Mitochondria-Targeted Antioxidant SkQ1: A Transcriptome Profiling Study

Figure 1

Differential gene expression analysis in the hippocampus of 18-month-old untreated OXYS rats and the influence of long-term treatment with SkQ1. (a) The number of DEGs () in control and SkQ1-treated OXYS rats, as compared to Wistar rats, respectively. The number of genes—(b) involved in pathways (according to KEGG) and (c) associated with GO terms (according to DAVID)—that change expression in untreated OXYS rats compared to Wistar rats. GO terms are marked red if upregulated and green if downregulated.

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