Efficiently Capturing Mitochondria-Targeted Constituents with Hepatoprotective Activity from Medicinal Herbs

Figure 9

Effects of the hit compound on the mice of CCl₄-induced injury. ALT and AST in serum (a and b), liver index, SOD, GSH, and MDA in liver tissue (c–f), and Na⁺-K⁺-ATPase, Ca²⁺-Mg²⁺-ATPase, mPTP, MDA, and ∆Ψm in HM (g–k) were measured. Data were obtained from 5 independent experiments and are expressed as . The statistical significance of differences between groups was evaluated by one-way analysis of variance (ANOVA) using Dunnett’s method. , , and compared with the model control group under identical conditions. P12: praeruptorin B; SB: silybin.

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