Function, Oxidative, and Inflammatory Stress Parameters in Immune Cells as Predictive Markers of Lifespan throughout Aging

Figure 2

Redox parameters analysed in peritoneal leukocytes from mice throughout a longitudinal study: (a) catalase (Cat) activity; (b) glutathione peroxidase (GPx) activity; (c) glutathione reductase (GR) activities; (d) reduced glutathione (GSH) concentration; (e) superoxide anion concentration; (f) oxidized glutathione (GSSG) concentration; (g) GSSG/GSH ratio; (h) MDA concentration. A: adult mice (40 weeks old; ); M: mature mice (56 weeks old; ); O: old mice (72 weeks old; ); VO: very old mice (96 weeks old; ); LG: long-lived mice (120 weeks old; ). ; ; with respect to the group of mice that die before the next age point (Student’s -test for independent samples). a: , aa: with respect to adult mice that reach high longevity; b: , bb: with respect to mature mice that reach high longevity; c: with respect to old mice that reach high longevity; d: , dd: with respect to very old mice that reach high longevity (Student’s -test for paired samples).

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