Research Article
NADPH Oxidase Hyperactivity Contributes to Cardiac Dysfunction and Apoptosis in Rats with Severe Experimental Pancreatitis through ROS-Mediated MAPK Signaling Pathway
Figure 6
Effects of Nox inhibition on pancreatic histopathology and proinflammatory cytokines after 24 h SAP induction. Representative micrographs of HE-stained sections of rat pancreatic tissue from different groups; images were taken under 200x magnification (a). Histology severity score of pancreas (b). Amylase (U/L) (c). Interleukine-1 beta (IL-1β) (d). Tumor necrosis factor alpha (TNF-α) (e). Endotoxin (ng/mL) (f). Endothelin-1 (ET-1) (g). Data are presented as , rats per group. SO, sham operation; SAP, severe acute pancreatitis; SAP-APO, SAP+apocynin; APO-CON, apocynin control. compared with the SO group. compared with the SAP group.
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