Maggot Extracts Alleviate Inflammation and Oxidative Stress in Acute Experimental Colitis via the Activation of Nrf2

Figure 4

The maggot extracts reduce oxidative stress and inflammation in mice with DSS-induced colitis via activation of the Nrf2 pathway. Mice were treated as explained in Figure 2. Colonic levels of SOD (a), MPO (b), GSH-Px (c), and MDA (d) were examined by chemical chromatometry. Serum levels of proinflammatory cytokine including TNF-α (e), IL-6 (f), and IL-10 (g) were measured with ELISA. Data are expressed as the . , , and ; ns = no significance.

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