The Nrf2/HO-1 Axis as Targets for Flavanones: Neuroprotection by Pinocembrin, Naringenin, and Eriodictyol

Figure 1

Structures of flavanones and related compounds. Pinocembrin, naringenin, and eriodictyol differ from each other by the degree of oxygenation in the B ring. Notice the difference between flavanones and flavones by the presence of the C2-C3 bond in the latter while flavonols possess further oxygenation at the C-3 position.