[Retracted] Apatinib Promotes Apoptosis of Pancreatic Cancer Cells through Downregulation of Hypoxia-Inducible Factor-1<i>α</i> and Increased Levels of Reactive Oxygen Species

<div>Apatinib induced apoptosis of pancreatic cancer cells. (a) Following the treatment of CFPAC-1 and SW1990 cells with various concentrations of apatinib (0, 8, and 16 <i>μ</i>M) for 24 h, these cells were stained using annexin V-FITC/PI and assessed by FACS analysis. (b) The quantitative analysis of the apoptotic cell numbers is shown. (c) The protein levels of Bcl-2, Bax, caspase-3, and cleaved caspase-3 are shown. All experiments were performed in triplicate. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: [Retracted] Apatinib Promotes Apoptosis of Pancreatic Cancer Cells through Downregulation of Hypoxia-Inducible Factor-1<i>α</i> and Increased Levels of Reactive Oxygen Species 

Figure 4 | [Retracted] Apatinib Promotes Apoptosis of Pancreatic Cancer Cells through Downregulation of Hypoxia-Inducible Factor-1α and Increased Levels of Reactive Oxygen Species 