Research Article

Active Constituent in the Ethyl Acetate Extract Fraction of Terminalia bellirica Fruit Exhibits Antioxidation, Antifibrosis, and Proapoptosis Capabilities In Vitro

Figure 5

Effect of GA on (a) PDGFR, (b) CTGF, (c) NF-κB, (d) MMP-2, (e) TIMP-1, (f) TIMP-2, (g) α-SMA, (h) Bcl-2, and (i) Bax gene expression in HSC-T6 cells. Cells were treated with GA at various concentrations (12.5, 25, and 50 μg/mL) for 24 h. Cells were treated with 0.1% DMSO as a vehicle control. Real-time PCR was performed to detect mRNA levels of target genes. Results are presented as relative changes normalized to GAPDH. , , and .
(a)
(b)
(c)
(d)
(e)
(f)
(g)
(h)
(i)