DpdtbA-Induced Growth Inhibition in Human Esophageal Cancer Cells Involved Inactivation of the p53/EGFR/AKT Pathway
p53 autophagic degradation regulated its downstream targets, (a, b) Kyse 450 cells and (c, d) Kyse 150 cells. (a, c) Western blotting analyses of alteration in the p53/EGFR/AKT axis and stub1-mediated autophagy relative proteins, the condition was as indicated. (b, d) Quantitative analyses of alteration of the expression of the p53/EGFR/AKT axis and LC3-II as well as stub1. CQ = chloroquine. Quantitative analyses of those proteins from Kyse 450 and Kyse 150 cells were performed from twice measurements. ,##,$$,&&,%%,,###,$$$,&&&,%%%.
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