Oxidative Medicine and Cellular Longevity / 2019 / Article / Fig 10

Research Article

DpdtbA-Induced Growth Inhibition in Human Esophageal Cancer Cells Involved Inactivation of the p53/EGFR/AKT Pathway

Figure 10

p53 autophagic degradation regulated its downstream targets, (a, b) Kyse 450 cells and (c, d) Kyse 150 cells. (a, c) Western blotting analyses of alteration in the p53/EGFR/AKT axis and stub1-mediated autophagy relative proteins, the condition was as indicated. (b, d) Quantitative analyses of alteration of the expression of the p53/EGFR/AKT axis and LC3-II as well as stub1. CQ = chloroquine. Quantitative analyses of those proteins from Kyse 450 and Kyse 150 cells were performed from twice measurements. ,##,$$,&&,%%, ,###,$$$,&&&,%%%.

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