Early Kidney Damage Markers after Deferasirox Treatment in Patients with Thalassemia Major: A Case-Control Study

Table 4

Comparison of blood renal parameters in 3 age groups.

			Study group
			Deferoxamine	Deferasirox	Control
			Mean ± SD	Mean ± SD	Mean ± SD	value
Age	Under 18 years old ()	GFR			—	0.159
		BUN				0.161
		CREA				0.048
		Cystatin C				0.593
		GFR based on Cystatin				0.416
	18 to 25 years old ()	GFR				0.053
		BUN				0.002
		CREA				0.103
		Cystatin C				0.159
		GFR based on Cystatin				0.166
	25 to 35 years old ()	GFR				0.038
		BUN				0.213
		CREA				0.137
		Cystatin C				0.233
		GFR based on Cystatin				0.233

Kruskal-Wallis test; ANOVA test; GFR: glomerular filtration rate; BUN: blood urea nitrogen; CREA: creatinine.