Soy Isoflavones Ameliorate Metabolic and Immunological Alterations of Ovariectomy in Female Wistar Rats: Antioxidant and Estrogen Sparing Potential

Table 2

Effect of soy isoflavones on feed intake (g/day/female), cumulative feed intake (g/female), weight gain (g/week), cumulative weight gain (g), and relative thymus and spleen weight (g%) among experimental groups.

Parameters		G1 (OVX/casein)	G2 (OVX/soy)	G3 (sham/casein)
Feed intake (g/day/female)	1st week	19.34 ± 1.11^a	17.20 ± 1.17^a	12.57 ± 0.68^b
	2nd week	18.75 ± 1.20^a	12.92 ± 0.86^b	11.65 ± 1.15^b
	3rd week	17.40 ± 0.67^a	14.63 ± 0.56^ab	12.87 ± 1.5 1^b
	4th week	16.42 ± 0.84^a	16.22 ± 1.03^a	11.77 ± 1.33^b
	5th week	21.93 ± 2.77^a	18.51 ± 0.80^ab	13.21 ± 1.39^b
	6th week	21.97 ± 3.44^a	18.37 ± 0.95^ab	13.80 ± 1.42^b
	7th week	21.33 ± 1.36^a	16.68 ± 3.14^a	9.75 ± 0.57^b
Cumulative feed intake (g/female)		956.22 ± 6.15^a	801.47 ± 5.41^b	599.48 ± 11.55^c
Weight gain (g/week)	2nd week	19.70 ± 1.08^a	11.73 ± 1.91^b	9.47 ± 1.28^b
	3rd week	10.45 ± 1.58^a	10.65 ± 0.88^a	8.90 ± 1.10^a
	4th week	12.19 ± 1.11^a	8.02 ± 0.80^b	5.37 ± 0.98^b
	5th week	7.08 ± 1.12^a	6.73 ± 0.63^a	5.73 ± 0.37^a
	6th week	6.32 ± 0.81^a	3.62 ± 0.40^b	2.97 ± 0.49^b
	7th week	5.33 ± 0.96^a	1.05 ± 0.52^b	1.07 ± 0.47^b
Cumulative weight gain (g)		44.12 ± 5.13^a	31.60 ± 5.01^b	23.45 ± 2.39^b
Relative weight (g%)	Thymus	0.35 ± 0.04^a	0.16 ± 0.02^b	0.32 ± 0.05^a
	Spleen	0.58 ± 0.04^a	0.50 ± 0.09^a	0.45 ± 0.06^a

^a-cMeans in the same row with different superscripts are significantly different (); values are presented as .