Soy Isoflavones Ameliorate Metabolic and Immunological Alterations of Ovariectomy in Female Wistar Rats: Antioxidant and Estrogen Sparing Potential

Table 4

Effect of soy isoflavones on lymphocyte transformation test (LTT), nitric oxide (NO), total antioxidant capacity (TAC), malondialdehyde (MDA), and inflammatory mediators among experimental groups.

Parameters	G1 (OVX/casein)	G2 (OVX/soy)	G3 (sham/soy)
LTT	0.65 ± 0.06^a	0.27 ± 0.04^b	0.51 ± 0.06^a
NO (μM/L)	29.41 ± 0.85^a	21.29 ± 0.91^b	21.84 ± 0.66^b
TAC (mM/L)	0.34 ± 0.12^a	0.82 ± 0.08^b	0.72 ± 0.04^b
MDA (nM/L)	1.97 ± 0.13^a	1.61 ± 0.07^b	1.53 ± 0.09^b
TNF-alpha (pg/mL)	8.99 ± 0.30^a	5.73 ± 0.56^b	5.25 ± 0.46^b
IL-2 (pg/mL)	5.74 ± 0.54^a	3.54 ± 0.27^b	3.39 ± 0.39^b
COX-2 (ng/L)	9.75 ± 0.42^a	6.70 ± 0.59^b	7.50 ± 0.44^b
CRP (mg/L)	1.56 ± 0.03^a	1.09 ± 0.07^b	1.04 ± 0.08^b

^a-bMeans in the same row with different superscripts are significantly different (); values are presented as .