Cicadidae Periostracum, the Cast-Off Skin of Cicada, Protects Dopaminergic Neurons in a Model of Parkinson’s Disease

Figure 5

Effects of CP on MPTP-induced Nurr1 and neurotrophic proteins. Seven days after the last MPTP treatment, Nurr1 levels were measured by IHC in dopaminergic neurons (a, b) and western blotting in the SNPC (a). Representative photomicrographs of the SNPC were taken (c). The expressions of Nurr1, TH, DDC, DAT, and VMAT2 were detected by western blotting using specific antibodies in the SNPC (d). β-Actin protein was used as an internal control. Bar graphs represent the relative expression of Nurr1 (a), TH (e), DDC (f), DAT (g), and VMAT2 (h) for (d). Values shown represent . and compared with the control group and and compared with the MPTP-treated group.

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