Oxidative Medicine and Cellular Longevity / 2019 / Article / Fig 5

Research Article

Reactive Oxygen Species Are Involved in the Development of Gastric Cancer and Gastric Cancer-Related Depression through ABL1-Mediated Inflammation Signaling Pathway

Figure 5

CMS facilitated the development of GC, accompanied with dysregulated activities of ABL1 and the inflammation signaling pathway. (a) CMS leads to the development of GC. Tumor growth curve and tumor weight indicated that CMS leads to the development of GC (). (b) ABL1 and inflammation factors including NF-κB1, STAT3, IL-1β, IL-6, and COX2 were dysregulated in tumor tissues of CMS-induced PDX mice ().

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