Antimetabolic Syndrome Effect of Phytosome Containing the Combined Extracts of Mulberry and Ginger in an Animal Model of Metabolic Syndrome

Table 2

The effect of various doses of PMG on metabolic parameters.

Parameters	ND+vehicle	HCHF+vehicle	HCHF+VitaminC	HCHF+Simvastatin	HCHF+PMG50	HCHF+PMG100	HCHF+PMG200
Body weight gain (%)		^a
Cholesterol (mg/dl)		^aa
Triglyceride (mg/dl)		^aaa
LDL-C (mg/dl)		^aaa
HDL-C (mg/dl)		^aa
Atherogenic index		^aaa
Plasma glucose AUC (mg h/dl)		^aa
HOMA-IR		^aaa
ACE (units/mg protein)		^aaa		^aa,

Data are presented as (/group). ^{a, aa, aaa} value < 0.05, 0.01, and 0.001, respectively, compared to naïve control which received ND and vehicle and value < 0.05, 0.01, and 0.001, respectively, compared to metabolic syndrome rats which received HCHF and vehicle. ND: normal diet; HCHF: high-carbohydrate high-fat diet; VitaminC: vitamin C at a dose of 250 mg·kg^-1 BW; Simvastatin: simvastatin at a dose of 1.3 mg·kg^-1 BW; PMG50, PMG100, and PMG200: the phytosome containing the combined extracts of mulberry and ginger at a dose of 50, 100, and 200 mg·kg^-1 BW, respectively.