Antimetabolic Syndrome Effect of Phytosome Containing the Combined Extracts of Mulberry and Ginger in an Animal Model of Metabolic Syndrome

Table 3

The effect of various doses of PMG on adipose tissue alterations.

Parameters		ND+vehicle	HCHF+vehicle	HCHF+VitaminC	HCHF+Simvastatin	HCHF+PMG50	HCHF+PMG100	HCHF+PMG200
Size of adipocyte (μm)	Visceral area		^aaa
	Subcutaneous area		^aaa
Density of adipocyte (adipocytes/225 μm^2)	Visceral area		^aaa
	Subcutaneous area		^aaa
Adiposity index (AI) (%)	Visceral area		^aaa
	Subcutaneous area
Weights of white adipose tissues (g/kg BW)			^aaa
	Subcutaneous area		^aa

Data are presented as (/group). ^{aa, aaa} value < 0.01 and 0.001, respectively, compared to naïve control which received ND and vehicle and value < 0.05, 0.01 and 0.001, respectively, compared to metabolic syndrome rats which received HCHF and vehicle. ND; normal diet; HCHF: high-carbohydrate high-fat diet; VitaminC: vitamin C at a dose of 250 mg·kg^-1 BW; Simvastatin: simvastatin at a dose of 1.3 mg·kg^-1 BW; PMG50, PMG100, and PMG200: the phytosome containing the combined extracts of mulberry and ginger at a dose of 50, 100, and 200 mg·kg^-1 BW, respectively.