Redox Balance Correlates with Nutritional Status among Patients with End-Stage Renal Disease Treated with Maintenance Hemodialysis
Table 1
Demographic data and selected laboratory results in the ESRD patients and control group.
Laboratory parameters
ESRD patients ()
Control group ()
Reference range
Age (years)
≤0.001
Not applicable
Males (, %)
60 (61.9)
17 (40.5)
0.023
Not applicable
Albumin (g/L)
39.4 (36.4–42.8)
44.5 (40.3–47.0)
<0.001
35–52
Prealbumin (g/L)
0.27 (0.22–0.32)
No data
—
0.20–0.40
CRP (mg/L)
5.75 (2.2–13.7)
1.45 (1.0–1.4)
≤0.001
<5
PLT (×103/μL)
0.005
125–340
WBC (×103/μL)
6.5 (5.1–7.8)
5.8 (5.3–6.8)
0.267
4–10
Total cholesterol (mmol/L)
<0.001
3.2–5.2
LDL cholesterol (mmol/L)
<0.001
0.2–3.4
HDL cholesterol (mmol/L)
0.022
0.9–3.0
Triglycerides (mmol/L)
1.5 (1.2–2.2)
1.9 (1.6–2.3)
0.210
0.2–2.3
Bilirubin (μmol/L)
8.5 (6.8–10.3)
10.1 (8.7–17.2)
0.014
0–21
Uric acid (μmol/L)
≤0.001
F: 143.0–340.0
M: 202.0–416.0
Total calcium (mmol/L)
1.89 (1.18–2.27)
No data
—
2.15–2.55
Phosphate (mmol/L)
2.50 (1.65–4.50)
No data
—
0.81–1.45
iPTH (pg/mL)
174.4 (75.4–410.7)
No data
—
14.9–56.9
Iron (μmol/L)
11.80 (9.12–15.00)
No data
—
5.83–34.50
TIBC (μmol/L)
No data
—
40.8–76.6
GPS
0 (, %)
56 (57.7)
39 (92.9)
1 (, %)
25 (25.8)
3 (7.1)
<0.001
0
2 (, %)
11 (11.3)
0
CRP/PRE
0.019 (0.008–0.0587)
No data
—
No data
Glutathione peroxidase (U/L)
≤0.001
No data
Glutathione reductase (U/L)
76.7 (66.7–98.3)
100.7 (91.0–111.6)
≤0.001
No data
FRAP (mmol/L)
0.027
No data
Superoxide dismutase (U/mL)
13.2 (9.8–17.5)
19.4 (13.6–23.9)
0.002
No data
LDL—low-density lipoprotein; HDL—high-density lipoprotein; iPTH—intact parathyroid hormone; PLT—platelet counts; WBC—white blood cells; TIBC—total iron binding capacity; GPS—Glasgow Prognostic Score; PRE—prealbumin; CRP—C-reactive protein; F—females; M—males; FRAP—ferric reducing antioxidant power. Due to local differences in patient monitoring, lipid profiles and iPTH were only available for 44 patients treated in Rzeszow, Poland.
