Research Article

H2S Protects against Cardiac Cell Hypertrophy through Regulation of Selenoproteins

Figure 1

H2S or H2Se protects from H2O2-induced cell death. (a) Effect of H2S on cell viability. H9C2 cells were incubated with NaHS (0-1000 μM) for 24 hours, and cell viability was measured with the MTT assay. (b) Effect of H2Se on cell viability. H9C2 cells were incubated with Na2Se (0-10 μM) for 24 hours, and cell viability was measured with the MTT assay. versus control. (c) H2S or H2Se reverses H2O2-inhibited cell viability. H9C2 cells were treated with/without NaHS (30 μM) or Na2Se (0.3 μM) for 30 minutes prior to incubation with H2O2 (0-1000 μM) for 24 hours. vs. control; # vs. H2O2 treatment alone in the same group. .
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