Research Article

miR-146a-5p Mediates Intermittent Hypoxia-Induced Injury in H9c2 Cells by Targeting XIAP

Figure 3

miR-146a-5p silence alleviates IH-induced injury in H9c2 cells. Cells were transfected with miR-146a-5p mimics, miR-146a-5p inhibitor, and corresponding scrambled control. Cells without treatment were acted as control. (a–e) Cell apoptosis by flow cytometry analysis. (f) Cell viability by a Cell Counting Kit-8. (g, h) Expression levels of apoptosis-related proteins by western blot analysis. Relative protein levels are presented as the average expressions normalized to actin. IH: intermittent hypoxia; . (Data are presented as the of three independent experiments. , , and ).
(a)
(b)
(c)
(d)
(e)
(f)
(g)
(h)