Sex Differences in Age-Associated Type 2 Diabetes in Rats—Role of Estrogens and Oxidative Stress

Figure 3

Metabolic profile shows that type 2 diabetes has a very high impact in the metabolism, and there are sex differences. Role of estrogen replacement therapy. (a) Metabolic profile of male GK (black triangle), female GK (gray triangle), young male (black circle), young female (gray circle), old male (black square), and old female (gray square). (b) Comparison of the metabolic profile of male GK (black triangle) and female GK (gray triangle). (c) Comparison of the metabolic profile of female GK controls (dark triangle) (), ovariectomized female GK (gray triangle) (), and ovariectomized female GK + estradiol replacement (white triangle) ().

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