Oxidative Medicine and Cellular Longevity / 2019 / Article / Fig 2

Research Article

Total Polysaccharides of Lily Bulb Ameliorate Menopause-Like Behavior in Ovariectomized Mice: Multiple Mechanisms Distinct from Estrogen Therapy

Figure 2

The effects of estradiol and TPLB on the expression levels of estrogen receptors, ERα and ERβ, in the uterus and brain regions after coadministration with ICI182,780. Representative images indicating the expression levels of ERα and ERβ and their quantification analysis in the uterus (a, b), hypothalamus (c, d), hippocampus (e, f), and prefrontal cortex (g, h). Data are expressed as () and examined with one-way ANOVA, followed by post hoc Sidak’s multiple comparison test: , , and vs. the sham group; #, ##, and ### vs. the OVX group; &, &&, and &&& vs. the E2 group or TP group. (i, j) The effects of TPLB on the ability of ERα binding (a) and ERβ binding (b) in vitro. Data are expressed as () and examined with one-way ANOVA, followed by post hoc Dunnett’s test: , , and vs. the control group.
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