Cardiac Rehabilitation Increases SIRT1 Activity and β-Hydroxybutyrate Levels and Decreases Oxidative Stress in Patients with HF with Preserved Ejection Fraction
Changes in control and ET-CR groups of Sirt1 activity, β-hydroxybutyrate, Ox-LDL levels, and TEAC from baseline to 4 weeks after the study start. The ET-CR was able to induce a significant increase in Sirt1 activity (a) and β-hydroxybutyrate (βOHB) (b) (both, ); a reduction in Ox-LDL (c) () and increased levels of antioxidant response measured by TEAC assay (d) (), as showed by the difference between the levels after 4 weeks minus the levels at baseline.
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