Oxidative Medicine and Cellular Longevity / 2019 / Article / Fig 2

Research Article

Cardiac Rehabilitation Increases SIRT1 Activity and β-Hydroxybutyrate Levels and Decreases Oxidative Stress in Patients with HF with Preserved Ejection Fraction

Figure 2

Changes in the control and ET-CR groups of Sirt1 activity, NAD+, NADH levels, and NAD+/NADH ratio from baseline to 4 weeks after the study start. The ET-CR was able to induce a significant increase in NAD+ (a), Sirt1 activity (b), and NAD+/NADH ratio (c) (all ), associated with a reduction in NADH levels (d) (), expressed as the difference between the levels after 4 weeks minus the levels at baseline.

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.