Research Article

Cardiac Rehabilitation Increases SIRT1 Activity and β-Hydroxybutyrate Levels and Decreases Oxidative Stress in Patients with HF with Preserved Ejection Fraction

Table 1

Main characteristics of total population and ET-CR group at baseline.

VariablesTotal populationCtrET-CR

Age (years), 0.357
BMI (kg/m2), 0.154
SBP (mmHg), 0.443
DBP (mmHg), 0.511
EF (%), 0.117
LVEDD (mm)0.404
CAD, (%)14 (71.4)14 (70)36 (72)0.542
PTCA, (%)37 (52.9)11 (55)26 (52)0.516
CABG, (%)10 (14.3)3 (15)7 (14)0.59
Previous IMA, (%)47 (67.1)13 (65)(68)0.51
Valvular substitution, (%)3 (4.3)1 (5)2 (4)0.642
Smoking, (%)37 (52.9)9 (45)28 (56)0.285
Hypertension, (%)30 (42.9)8 (40)22 (44)0.487
Dislipidemia, (%)31 (44.3)9 (45)22 (44)0.574
Diabetes, (%)14 (20)4 (20)10 (20)0.619
COPD, (%)13 (18.6)4 (20)9 (18)0.545
Beta blockers64 (91.4)18 (90)46 (92)0.556
ACE inhibitors32 (45.7)9 (45)23 (46)0.576
ARBs9 (12.9)2 (10)7 (14)0.495
Diuretics20 (28.6)5 (25)15 (30)0.458
Ca2 antagonists7 (10)2 (10)5 (10)0.652
Aspirin56 (80)15 (75)41 (82)0.361
Anticoagulants33 (47.1)9 (45)24 (48)0.516
Oral hypoglycemics11 (15.7)4 (20)7 (14)0.385
Insulin5 (7.1)1 (5)4 (8)0.556
Statin53 (75.7)15 (75)38 (76)0.578

Data are expressed as the or number of subjects (%). BMI: body mass index; SBP: systolic blood pressure; DPB: diastolic blood pressure; EF: ejection fraction; LVEDD: left end diastolic diameter; CAD: coronary artery disease; PTCA: percutaneous transluminal coronary angioplasty; CABG: coronary artery bypass graft; COPD: chronic obstructive pulmonary disease; ARBs: angiotensin II receptor blockers.